; Bramante, C.M. ; Wolff, D.; Dreyhaupt, J.; Martin, N.; Staehle, H.J. ; Foxton, R.; Manoharan, A.; Watson, T.F. Int Endod J. This comparatively new biomaterial is claimed to possess properties similar to MTA and is currently being explored for vital pulp therapy procedures. However, the potential clinical relevance of the difference of 4.32% in the success rates of MTA and Ca(OH) 2 can be discussed. Giraud, T.; Jeanneau, C.; Rombouts, C.; Bakhtiar, H.; Laurent, P.; About, I. those of the individual authors and contributors and not of the publisher and the editor(s). Fathy, S. Remineralization ability of two hydraulic calcium-silicate based dental pulp capping materials: Cell-independent model. Simon, S.; Smith, A.J. On the other hand, it has been proven that the fluoride ion release of ACTIVA is lower than that of the conventional GI (Keta Molar Quick Aplicap, 3M ESPE, Saint Paul, MN, USA) and also than that of RMGI cement (VitremerTM, 3M-ESPE, Saint Paul, MN, USA) [, The company markets this product as a “light-cured resin-modified calcium silicate” (RMCS) combining uncompromised attributes of both composite and GI [, Comparing to both MTA and Biodentine, ACTIVA BioACTIVE represents a favorable setting time with no delay placing final restoration (, The bioactive properties of ACTIVA BioACTIVE products are based on a mechanism whereby the material responds to pH cycles and plays an active role in releasing and recharging of significant amounts of calcium, phosphate and fluoride [, Despite the fact that ACTIVA BioACTIVE products are RMGICs, the laboratory and clinical findings indicate that the self-adhesive ability of the material is not elucidated [, Considering the material’s characteristics, the application of ACTIVA BioACTIVE in direct and indirect pulp capping might be justified. help prevent the need for a re-entry procedure weeks later for removal of the residual caries, with further excavation steps. Epub 2012 Mar 31. Laurent, P.; Camps, J.; About, I. BiodentineTM induces TGF-β1 release from human pulp cells and early dental pulp mineralization. 2020 Oct 7;9(10):2241. doi: 10.3390/cells9102241. Yelamali, S.; Patil, A.C. ; Lim, K.C. ; Barud, H. Radiopacity and Chemical Assessment of New Commercial Calcium Silicate-Based Cements. ; Bernardineli, N.; Garcia, R.B. The authors declare no conflict of interest. ; Silva, R.; Letra, A. Camilleri, J. Tulumbaci, F.; Almaz, M.E. Where calcium hydroxide biomaterials were once considered the gold standard of capping materials, mineral trioxide aggregate (MTA) and calcium silicate (CS) are now … National Center for Biotechnology Information, Unable to load your collection due to an error, Unable to load your delegates due to an error. Properties of NeoMTA plus and MTA plus cements for endodontics. Chailertvanitkul, P.; Paphangkorakit, J.; Sooksantisakoonchai, N.; Pumas, N.; Pairojamornyoot, W.; Leela-apiradee, N.; Abbott, P.V. ; Zeferino, M.A. -, Stencel R., Kasperski J., Pakiela W., Mertas A., Bobela E., Barszczewska-Rybarek I., Chladek G. Properties of experimental dental composites containing antibacterial silver-releasing filler. [ Links ] 8. Therefore, those materials should constitute the objects of future studies, especially in terms of cytotoxicity, quality of induced dentin bridge and protocols for higher bond strength to tooth structure and final restoration. The major challenge for the modern approach in restorative dentistry is to induce the remineralization of hypomineralized carious dentine, and therefore, protecting and preserving the vital pulp. Odabaş, M.E. One study of indirect pulp capping recorded success rates of 98.3% and 95% using bioactive tricalcium silicate [Ca3SiO5]-based dentin substitute and light-activated calcium hydroxide [CA(OH)2]-based liner respectively. Septodont Biodentine Active Biosilicate Technology Scientific File. may include direct pulp capping, indirect pulp capping if the tissue is not fully exposed, and partial or total pulpotomy; this permits the preservation of the vitality of the tooth, its nociceptive functions, and the defense system of the body itself. Effect of smear layer deproteinizing on resin-dentine interface with self-etch adhesive. J Endod, 41 (2015), pp. Direct pulp capping is used when the pulp is visibly exposed (vital pulp exposure) due to caries, trauma, or iatrogenic insult such as accidental exposure during tooth preparation or caries removal. ; Saunders, W.P. ; Yousef, M.K. Direct pulp capping with mineral trioxide aggregate: An observational study. Tom As-Catal, C.J. Materials and methods: A longitudinal interventional single-blind randomized clinical trial was conducted on 94 children (7-12 years) with a deep carious lesion in one or more primary second molar and permanent first molar without the history of spontaneous pain indicated for indirect pulp capping (IPC) procedure. Keywords: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations. ; Hebling, J.; Hanks, C.T. Abuhaimed, T.S. 2009) and the PICO framework to address the following clinical questions: ‘Is direct pulp capping a clinically effective treatment for cariously exposed pulps with a diagnosis of reversible pulpitis and does success differ with different pulp capping materials?’ BaklandDirect pulp capping with mineral trioxide aggregate: an observational study. Kim, J.R.; Nosrat, A.; Fouad, A.F. • - Stimulate reparative dentin formation. 30. Evaluation of shear bond strength of a composite resin to white mineral trioxide aggregate with three different bonding systems-An in vitro analysis. ; Batra, M.; Saini, M. MTA versus Biodentine: Review of Literature with a Comparative Analysis. The effects of indirect pulp capping materials CASE REPORT. Asgary, S.; Parirokh, M.; Eghbal, M.; Brink, F. Chemical Differences between White and Gray Mineral Trioxide Aggregate. NIH According to available research, there is also insufficient evidence to support the use of TheraCal LC or ACTIVA BioACTIVE BASE/LINER in vital pulp therapy. G. Bogen, J.S. ; Lee, H.-S.; Choi, H.-J. ; Abrandabadi, A.N. Selecting the best materials for either of these pulp-capping processes is critical. TheraCal LC performs as an insulator/barrier and protectant of the Materials Used in Direct and Indirect Pulp Capping Historically, calcium hydroxide (Ca (OH) 2) has been considered the gold standard. As a response to the disadvantages of MTA, a new tricalcium silicate-based cement Biodentine (Septodont, France) was released in 2011. ; Tagami, J. Bortoluzzi, E.A. The bioavailability of calcium ions released form TheraCal LC is proven to be in the concentration range for potential stimulatory activity for dental pulp and odontoblasts, although still significantly lower than in the case of Biodentine [, The material seals the pulp capping site despite contact with dentinal or pulpal fluids, as its solubility is lower than ProRoot MTA, MTA Angelus and Biodentine (, Lack of cytotoxicity and biocompatibility are the significant factors referring to pulp capping agents which directly affect the clinical outcome. Materials (Basel). Methods for biomimetic remineralization of human dentine: A systematic review. The physical characteristics of resin composite–calcium silicate interface as part of a layered/laminate adhesive restoration. Li, X.; De Munck, J.; Van Landuyt, K.; Pedano, M.; Chen, Z.; Van Meerbeek, B. eCollection 2020. ; Pfefferle, T. Mineral Trioxide Aggregate or Calcium Hydroxide Direct Pulp Capping: An Analysis of the Clinical Treatment Outcome. Awawdeh, L.; Al-Qudah, A.; Hamouri, H.; Chakra, R.J. Outcomes of Vital Pulp Therapy Using Mineral Trioxide Aggregate or Biodentine: A Prospective Randomized Clinical Trial. Please note that many of the page functionalities won't work as expected without javascript enabled. ; Dehghan, H.; Tamiz, P.; Savadroodbari, M.M. Long-term Pulpal and Restorative Outcomes of Pulpotomy in Mature Permanent Teeth. Namely, iRoot BP (IBC, Burnaby, BC, USA) is deposited on preloaded syringes, while the iRoot BP Plus is available in jars and with a thicker consistency, and the iRoot FS was especially developed to set faster with final setting time of 57.0 ± 2.7 min [. ; Bjørndal, L.; Maltz, M.; Manton, D.J. ; Lee, S.H. Calcium hydroxide pastes: Classification and clinical indications. Response of human dental pulp capped with biodentine and mineral trioxide aggregate. Managing Carious Lesions: Consensus Recommendations on Carious Tissue Removal. 2020 Oct 29;8:580954. doi: 10.3389/fbioe.2020.580954. Hegde, S.; Sowmya, B.; Mathew, S.; Bhandi, S.H. Dispensed in a syringe with a small tip it is easy to place in even the deepest areas of the prep. NLM Get the latest public health information from CDC: https://www.coronavirus.gov, Get the latest research information from NIH: https://www.nih.gov/coronavirus, Find NCBI SARS-CoV-2 literature, sequence, and clinical content: https://www.ncbi.nlm.nih.gov/sars-cov-2/. ; Duarte, M.A.H. Our dedicated information section provides allows you to learn more about MDPI. The pulp healing process: From generation to regeneration. Schembri, M.; Peplow, G.; Camilleri, J. Rao, Q.; Kuang, J.; Mao, C.; Dai, J.; Hu, L.; Lei, Z.; Song, G.; Yuan, G. Comparison of iRoot BP Plus and Calcium Hydroxide as Pulpotomy Materials in Permanent Incisors with Complicated Crown Fractures: A Retrospective Study. ; Tomson, P.L. Brizuela, C.; Ormeño, A.; Cabrera, C.; Cabezas, R.; Silva, C.I. Omidi, B.R. Indeed, recent consensus reports have stated that the complete or nonselective carious removal is now considered overtreatment [, Six different bioactive materials have been described and compared: four calcium-silicate cements—ProRoot MTA (Dentsply Sirona, York, PA, USA), MTA Angelus (Angelus, Londrina, Brazil), RetroMTA (BioMTA, Seoul, Korea) and Biodentine (Septodont, Saint-Maur-des-Fossés, France); a light-cured calcium silicate-based material TheraCal LC (Bisco, Schaumburg, IL, USA); and a resin-modified glass-ionomer (RMGIC) with improved resilience and physical properties—ACTIVA BioACTIVE (Pulpdent Corporation, Watertown, MA, USA) [. Biological effects and washout resistance of a newly developed fast-setting pozzolan cement. Torabinejad, M.; Watson, T.F. ; Song, J.S. Pameijer, C.H. Oral Radiol. Nevertheless, calcium hydroxide has some drawbacks like tunnel defect during dentinal bridge formation, poor bonding to dentin, material resorption and mechanical instability. COVID-19 is an emerging, rapidly evolving situation. Yet, despite the possibility of immediate restoration placing after initial set, there is statistically significant increase in SBS when bonding with Biodentine after a 72-h maturation period [, Although Biodentine offers many advantages over MTA, it presented significantly lower SBS values than MTA to restorative materials, including composite (Filtek Z250, 3M, Saint Paul, MN, USA), compomer (Dyract XP®) and RMGI cement (Photac-Fil Quick Aplicap, 3M, Saint Paul, MN, USA) [. ; writing—original draft preparation, M.L.-S. and M.K. Fonseca, T.S. Current status of pulp capping with dentin adhesive systems: A review. Biodentine. Islam, I.; Kheng Chng, H.; Jin Yap, A.U. ; Schäfer, E.; Dammaschke, T. Shear bond strength of Biodentine, ProRoot MTA, glass ionomer cement and composite resin on human dentine ex vivo. HHS Katge, F.A. As in the other light-cured tricalcium silicate, incomplete resin photopolymerization may lead to free monomers’ release, and consequently to pulpal toxicity [, Development of minimally invasive biologically based therapies aimed at preservation of the pulp vitality remains the key theme within contemporary clinical endodontics. ; Foxton, R. ; Reis, J.M.S.N Dhillon, J.S a Analysis... To determine their Clinical efficacy, further studies are needed to support use of these pulp-capping is. Resin composite analyzing their fluoride release profiles a protective base/liner under composites, amalgams, cements, and a tricalcium. Mta for direct pulp capping procedures B. ; Walsh, L.J J Endod 41... 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