EPILEPSY is the most common chronic canine neurological disorder, affecting around 0.57% of dogs.1 Phenobarbital is the first-line treatment for canine epilepsy and is an effective monotherapy in 60-80% of dogs with idiopathic epilepsy, but phenobarbital alone does not achieve adequate seizure control in all cases.2 Potassium bromide (KBr) has been reported to be effective in the management … The authors did not find any studies in the published literature that evaluated the effects of KBr in reproductively active dogs. If any side effects begin to occur, it is important to immediately contact the veterinarian that prescribed the Potassium Bromide in order to obtain directions on how best to move forward. K•BroVet ® Chewable Tablets & Oral Solutions. Potassium Bromide (abbreviated as KBr) is often considered the first choice drug for any dogs with idiopathic epilepsy, and because it has no effect on the liver, is often chosen for dogs with liver damage. Keppra is available in different dosages, including 500-milligram and 750-milligram extended-release tablets. Potassium bromide may be used alone (as "monotherapy") or can be combined with other anti-medications. The best next step is for a drug company to seek FDA approval of potassium bromide for use as an anti-seizure medication in dogs. Context Menu. It is intended to aid in the management of dogs experiencing epileptic seizures. When we added Potassium Bromide we were able to cut the pheno by more than 60% which has reduced the liver damage to a point where we could discontinue the drugs that dealt with that! He let me know that Potassium Bromide can build up in the system to the point that it causes hind-end weakness. This drug inhibits abnormal neuron activity in the brain and thus reduces episodes of seizures. Phenobarbital, or PB, has also been used for years to treat seizures. is vital in order to safeguard the health and wellbeing of your dog. Increased hunger and thirst may be a side effect for dogs taking Potassium Bromide, or a combination of Phenobarbital and Potassium Bromide. The two most commonly used bromides are potassium bromide and sodium bromide. Potassium Bromide is a medication that some veterinarians prescribe to dogs, most often for dogs suffering from canine idiopathic epilepsy. Bromide toxicity encompasses many of the side effects listed above and can usually be stopped by reducing the dose. The goal of this study was to evaluate the efficacy of phenobarbital or potassium bromide (KBr) as add-on antiepileptic drugs for controlling dogs refractory to a maximum dose of imepitoin (30 mg/kg twice daily). In March 2012, they published the results of their review in the Journal of the American Veterinary Medical Association. K-BroVet requires a prescription from your veterinarian. Dogs receiving potassium bromide in combination with phenobarbital will commonly exhibit elevated serum pancreatic lipase immunoreactivity concentrations (cPLI) which may or may not be associated with clinical signs of pancreatitis. For dogs who can't tolerate potassium even when the dose is divided and given with food, sodium bromide may be an alternative. Tags: potassium bromide for dogs, potassium bromide for dogs side effects. A brain tumor in a dog can also present with these signs. As part of the approval process for an animal drug, a drug company traditionally would conduct laboratory-based studies to collect safety information on the drug. In cases of pancreatitis or dermatitis, symptomatic treatment may … When compared to phenobarbital, potassium bromide seems to be similarly effective and has fewer undesirable side effects. q 12 h for a period of 115 days. When bromide is used as the sole treatment for epilepsy in dogs, higher dosages (50–80 mg/kg/day) may be necessary. As with all medications, Potassium Bromide has potential side effects that may occur when taking it. Microchipping Could Save your Pet's Life. “Daisy,” an 8-year-old, female spayed Dalmatian with a history of idiopathic epilepsy, and her owner are in Exam Room 1. Active ingredient: Potassium Bromide. K-BroVet is available in liver flavored chewable tablets that are 250 mg or 500 mg strengths. Potassium and sodium bromide are drugs used to control seizures in your dog, but there can be side effects and toxicity in some cases. Symptoms of Bromide Toxicity in Dogs Stomach irritation (some sensitive dogs may need the splitting of the daily dose into two lots and given with food) Potassium bromide (KBr) is actually a chemical product, not a drug formulation.1-3,5-8,19-23 Potassium bromide has reasonable efficacy for treatment of seizures in dogs and may be used as a monotherapy or in combination with other anticonvulsants. 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